Rethinking dog domestication by integrating genetics, archeology, and biogeography

Abstract

Rethinking dog domestication by integrating genetics, archeology, and biogeography Greger Larson a,1, Elinor K. Karlsson b,c, Angela Perri a, Matthew T. Webster d, Simon Y. W. Ho e, Joris Peters f, Peter W. Stahl g, Philip J. Piperh,i, Frode Lingaasj, Merete Fredholmk, Kenine E. Comstockl, Jaime F. Modianom,n, Claude Schellingo, Alexander I. Agoulnikp, Peter A. Leegwaterq, Keith Dobneyr, Jean-Denis Vignes, Carles Vilàt, Leif Anderssond,u, and Kerstin Lindblad-Tohb,d a Durham Evolution and Ancient DNA, Department of Archaeology, University of Durham, Durham DH1 3LE, United Kingdom; bBroad Institute of MIT and Harvard, Cambridge MA 02142; cFaculty of Arts and Sciences Center for Systems Biology, Harvard University, Cambridge MA 02138; dScience for Life Laboratory Uppsala, Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden; eSchool of Biological Sciences, University of Sydney, Sydney NSW 2006, Australia; fVeterinary Sciences Department, Institute of Palaeoanatomy, Domestication Research and the History of Veterinary Medicine, Ludwig-Maximilian University, 80539 Munich, Germany; gDepartment of Anthropology, University of Victoria, Victoria, BC, Canada V8W 2Y2; hSchool of Archaeology and Anthropology, Australian National University, Canberra, Australian Capital Territory 200, Australia; iArchaeological Studies Program, University of the Philippines, Diliman, 1101, Quezon City, Philippines; jDepartment of Basic Sciences and Aquatic Medicine, Division of Genetics, Norwegian School of Veterinary Science, 0033 Oslo, Norway; kFaculty of Life Sciences, Division of Genetics and Bioinformatics, Department of Basic Animal and Veterinary Sciences, University of Copenhagen, 7-1870 Frederiksberg C, Denmark; lUniversity of Michigan-Dearborn, Dearborn, MI 48128; mDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108; nMasonic Cancer Center, University of Minnesota, Minneapolis, MN 55455; oDepartment of Animal Sciences, Swiss Federal Institute of Technology Zurich and Vetsuisse Faculty Zurich, University of Zurich, 8092 Zurich, Switzerland; pDepartment of Human and Molecular Genetics, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199; qDepartment of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, 3508 TD Utrecht, The Netherlands; r Department of Archaeology, University of Aberdeen, Aberdeen AB24 3UF, Scotland, United Kingdom; sDépartement “Ecologie et Gestion de la Biodiversité”, Muséum National d’Histoire Naturelle, “Archéozoologie, Archéobotanique: Sociétés, Pratiques et Environnements,” Centre National de la Recherche Scientifique-Institut Ecologie et Environement, F-75005 Paris, France; tConservation and Evolutionary Genetics Group, Doñana Biological Station, 41092 Seville, Spain; and uDepartment of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, SE-75123 Uppsala, Sweden