Population Genetic Data of 30 Insertion-Deletion Markers in the Polish Population
Abreu-Glowacka M, Pepinski W, Michalak E, Konarzewska M, Zak K, Skawronska M, Niemcunowicz-Janica A, Soltyszewski I, Krajewski P, Zaba C.
Abstract
(1) Background: Insertion-deletion (InDel) markers show the advantages of both short tandem repeats (STRs) and single nucleotide polymorphisms (SNPs) and are considered alternative markers in forensic genetics. (2) Methods: Allelic frequencies and corresponding forensic efficiency parameters of 30 autosomal polymorphic InDel loci included in the Investigator DIPplex kit (Qiagen) were obtained in a sample of 631 unrelated Polish individuals. Allelic frequency data were compared with those reported for selected populations (3) Results: All the loci conformed with Hardy-Weinberg equilibrium after applying a Bonferroni correction and no pair-wise significant linkage disequilibrium was detected. (4) Conclusions: DIPplex Kit differences were high among populations worldwide. The InDel markers are highly discriminating for human identification purposes in the Polish population. Keywords: Poland, population, InDels, Investigator DIPplex, forensic genetics
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